ea0021p221 | Endocrine tumours and neoplasia | SFEBES2009
Stovold Rachel
, Stevens Adam
, Ray David
, Sommers Paula
, Dive Caroline
, Blackhall Fiona
, White Anne
Small cell lung cancer (SCLC) is an aggressive neuroendocrine tumour that shows early metastasis and resistance to chemotherapy. Current biomarkers focus on prognosis and diagnosis but there is a need to find novel biomarkers, which could, for example, identify patients at risk of cerebral metastases.Pro-opiomelanocortin (POMC), the precursor of ACTH is a well-recognised biomarker of the ectopic ACTH syndrome1, of which SCLC is the most preval...